Scientists have learned about the ability of fish oil to help in the fight against type 2 diabetes
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- Scientists have learned about the ability of fish oil to help in the fight against type 2 diabetes
Omega-3 fatty acids contained in fish oil are able to reduce insulin resistance and suppress inflammation, even in type 2 diabetes, which occurs without obesity. This was reported on May 31 by Science Daily magazine with reference to the results of a study by Brazilian scientists from the Butantan Institute and the University of Cruzeiro do Sul.
During the experiment, experts studied the effect of fish oil on Goto-Kakizaki rats, which serve as a model for type 2 diabetes not associated with obesity. The rodents received the supplement at a dosage of 2 g per 1 kg of body weight three times a week for eight weeks. At the end of the experiment, the subjects recorded an improvement in blood sugar control, a decrease in the level of "bad" cholesterol and triglycerides, as well as a decrease in inflammatory markers.
Rui Kuri, Director of the Butantan Institute Educational Center, Professor of Interdisciplinary Postgraduate Research in Health Sciences at the University of Cruzeiro do Sul and coordinator of the study
We found that insulin resistance in these animals can be reduced by modulating the inflammatory response in such a way as to change the profile of protective cells [lymphocytes] from a pro-inflammatory state to an anti-inflammatory one. This process is similar to the reaction of people with obesity and insulin resistance to omega-3 fatty acid supplements.
According to the professor, the process is similar to the reaction of obese people to omega-3 supplements. Scientists have found that systemic inflammation is a key factor in diabetes even in the absence of excess weight. According to various estimates, from 10 to 20% of patients with this disease worldwide are not obese, but the mechanisms of their disease development have been less studied.
Tiago Bertola Lobato, a participant in the study, emphasized that fish oil changed the pro-inflammatory profile to a protective one, which led to an increase in the number of regulatory T cells. According to him, it was this effect of omega-3 on lymphocytes that could trigger a decrease in insulin resistance.
The authors emphasize that the results of preclinical animal trials require confirmation in human clinical trials. Although one 2025 study showed a decrease in fasting insulin levels in healthy adults when taking fish oil, scientists have yet to determine the exact dosages and the most effective types of fatty acids for treating diabetic patients without obesity.
On May 27, Medical Xpress magazine ruled out the harm of natural trans fats in milk for heart health. According to the researchers, they behave differently in the body compared to their industrial counterparts and, unlike artificial compounds directly related to heart disease, they do not pose a threat to health.
Переведено сервисом «Яндекс Переводчик»
