Scientists have found a way to slow down the development of neurodegenerative diseases
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- Scientists have found a way to slow down the development of neurodegenerative diseases
Scientists at Sechenov University have confirmed the neuroprotective effect of the HSP70 heat shock protein in diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease and Alzheimer's disease. The results open up new opportunities for the development of drugs aimed at protecting the brain at the molecular level, scientists told Izvestia.
In a series of studies, a team of specialists studied the effect of one of the key proteins of the HSP70 family on the development of neurodegeneration in transgenic mice. One of the latest experiments used mice with a model of the neurodegenerative process— a form of the disease similar to ALS in humans.
"We have observed that overexpression of HSP70 helps cells better cope with the accumulation of pathological proteins, prevents their aggregation and protects neurons from premature death," said Gennady Piavchenko, associate professor of the Department of Human Anatomy and Histology at the N. V. Sklifosovsky Institute of Clinical Medicine.
The results open up prospects for the development of drugs capable of activating the protective functions of these proteins.
Read more in the exclusive Izvestia article:
The power of shock: promising dementia drug has been tested on animals
Переведено сервисом «Яндекс Переводчик»
