Russian scientists have created a highly accurate method for the diagnosis of chronic heart failure

Doctors of the Department of Hospital Therapy No. 1 at Sechenov University, together with scientists from the Center for Biopharmaceutical Technologies and Metabolic Analysis at the First Moscow State Medical University, have developed a new method for diagnosing chronic heart failure by analyzing the metabolic profile. This is a comprehensive analysis that provides information about the metabolic state of the body.

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"In search of more reliable diagnostic solutions, we tried to use an alternative method for detecting heart failure — metabolomic profiling, that is, the analysis of metabolites — products of metabolism occurring in the body," explained Maria Kozhevnikova, the author of the scientific work, professor of the department, MD, to Izvestia.

In addition, the scientists evaluated different variants of heart failure — with a preserved left ventricular ejection fraction and a low ejection fraction. There are different approaches to treatment for them, the doctors said. Therefore, it was important to determine the metabolomic profile for each individual variant.

Determining the patient's metabolic profile and phenotype can help improve the management of chronic heart failure. Some have signs of inflammation, while others have signs of free radical release. The therapy in this case may vary, the researcher noted.

Read more in the exclusive Izvestia article:

The phenotype of that: scientists will increase the accuracy of diagnosis of heart failure