New lithograph will help create artificial organs

MIPT specialists have created a unique Russian lithograph for the production of three-dimensional microstructures with up to 150 elements and a resolution of 350 nanometers. These scales make it possible, for example, to shoe a flea.

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With the help of the invention, it is possible to print micromechanical devices or frameworks for growing artificial biological organs with a given geometry.

"For the cultivation of bioengineered objects, for example, artificial organs, a skeleton system is first produced, on which cells capable of forming tissue are already applied. A special biocompatible polymer is used to produce the frame. Due to this design, we can arrange cells in a certain way so that they can better interact with proteins or other cells. This is important for growing various biological structures," said Danila Kolymagin, chief designer of the project and head of the Optical Lithography Design Bureau.

The development also makes it possible to make miniature filters that separate some cells from others. In this way, it is possible to isolate certain components in biological substances or to separate healthy and diseased cells. During one of the experiments, experts tested how membranes of various shapes let through or, conversely, delay human embryonic kidney cells.

Read more in the exclusive Izvestia article.:

Nanoprinting intelligence: new lithograph will help create artificial organs