Russian bioengineers will start creating eardrums and nasal septums


Sechenov University will launch production of personalized biomedical cellular products (BMPC) in 2025. The university told Izvestia that BMPCs for the restoration of vocal folds and tympanic membranes are now fully ready for use in clinical practice.
The procedures for patients who will be recommended treatment with the use of such technologies are almost the same as they are now. They will need to see a doctor and undergo an examination, just as they would in preparation for any other surgery. If there are no contraindications, a small fragment of fatty tissue will be taken from the patient at the Clinical Center for the fabrication of the BMKP. After the doctor receives the finished product, he will inject it into the patient's body during surgery - for example, in the form of an injection.
According to Peter Timashev, scientific director of the Biomedicine Science and Technology Park (NTPB), during this time scientists have worked out the technology of producing spheroids - "balls" from patient's cells that secrete a cocktail of biologically active substances: growth factors, anti-inflammatory factors.
"They act as a regulator of regeneration and stimulate the formation of not scar tissue, but one that will be close to normal. The researchers also created bioequivalents for the replacement of the eardrum and vocal cords and conducted a number of experiments on animals that demonstrated the effectiveness of such therapy," the specialist said.
Production of cellular products will be organized on the basis of clean rooms of NTPB. Biobank specialists will take care of logistics, who will carry out the initial evaluation and registration of biomaterial, provide incoming control and transfer selected samples to production.
Read more in the exclusive material of Izvestia:
Cell forecast: Russia will start producing eardrums and nasal septums
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