A new bioprinter to combat non-healing wounds will be tested on minipigs

The V.A. Rakhmanov Clinic of Skin and Venereal Diseases, the Institute of Regenerative Medicine and the Design Center for Flexible Bioelectronics at Sechenov University are developing a portable Biogan bioprinter for bioprinting tissue equivalent of skin, which will be effective for treating non-healing or poorly healing ulcers, including those of diabetic nature.

Emergency Opinion: AI will track patients in the ICU

The technology will be presented at the Russian Healthcare Week in Moscow

To test the system, the scientists plan to conduct an experiment on minipigs at the Laboratory of Regenerative Veterinary Medicine at Sechenov University. The research is being conducted with financial support from a grant from the Russian Science Foundation.

"The aim of the project is to create an approach to the restoration of complexly organized tissue complexes. This is a complex task, for the solution of which our team has developed combined bioinks, a portable bioprinter "Biogan" and a photobiomodulator for exposure of tissues to low-intensity radiation in the red and near-infrared range to accelerate regeneration processes", - said the head of the laboratory of applied microfluidics of Sechenov University, project leader Anastasia Shpichka.

To create combined bioinks for the printer, they use hydrogel with spheroids - aggregates of cells that are used as building blocks, as well as extracellular vesicles that have a pronounced pro-regenerative and anti-inflammatory potential. As part of such inks, cells exchange various signaling molecules and develop as in natural tissue.

Read more in the exclusive material of Izvestia:

Printing with intelligence: a bioprinter has been created to fight non-healing wounds